海南省腫瘤醫(yī)院

臨床檢驗診斷學(xué)、臨床分子診斷、實驗室質(zhì)量管理、醫(yī)學(xué)遺傳學(xué)、遺傳咨詢、法醫(yī)物證鑒定（親權(quán)鑒定）。

一、腫瘤發(fā)病機(jī)制及腫瘤靶向藥物與早期篩查試劑盒研發(fā)

二、腸道微生態(tài)與腫瘤關(guān)系的機(jī)制研究

三、干細(xì)胞臨床轉(zhuǎn)化應(yīng)用研究

四、各類病原體早期診斷試劑盒研發(fā)

五、產(chǎn)前篩查與產(chǎn)前診斷新技術(shù)與試劑盒研究

六、重大遺傳病診斷與治療研究

現(xiàn)任：

一、海南省抗癌協(xié)會腫瘤標(biāo)志與分子醫(yī)學(xué)專業(yè)委員會主任委員

二、海南省遺傳學(xué)會第六屆理事會常務(wù)理事兼秘書長

三、海南省醫(yī)學(xué)會檢驗專業(yè)委員會青年委員會常務(wù)副主任委員

四、海南省司法鑒定協(xié)會法醫(yī)物證專業(yè)委員會副主任委員

五、海南省醫(yī)學(xué)會醫(yī)學(xué)遺傳學(xué)分常務(wù)委員

六、海南省臨床檢驗專業(yè)醫(yī)療質(zhì)量控制中心專家委員會委員（2023.06-2024.12）

七、中國非公立醫(yī)療機(jī)構(gòu)協(xié)會檢驗醫(yī)學(xué)分會第一屆委員會首席專家兼常務(wù)委員

八、海南省抗癌協(xié)會第一屆神經(jīng)內(nèi)分泌腫瘤專業(yè)委員會常務(wù)委員

九、海南省免疫學(xué)會第三屆理事會青年工作委員會副主任委員

曾任：

一、中華醫(yī)學(xué)會檢驗分會青年委員會委員

二、海南省醫(yī)學(xué)會檢驗專業(yè)委員會青年委員會常務(wù)副主任委員

一、Xinping Chen, Weihua Xu, Shengmiao Fu*. Association between metoprolol and prognosis of COVID-19 patients. Journal of the American College of Cardiology，2022,1(79):e7. (SCI IF:24.094)

二、Xinping Chen; Weihua Xu; Zhichao Ma; Juan Zhu; Junjie Hu; Xiaojuan Li; Shengmiao Fu ; TTN -AS1 accelerates the growth and migration of nasopharyngeal carcinoma cells via targeting miR-876 -5p/NETO2, Molecular Therapy Oncolytics, 2021, 24: 535-546. (SCI IF:7.2)

三、Xinping Chen, Weihua Xu, Zhichao Ma, Juan Zhu, Junjie Hu, Xiaojuan Li, and Shengmiao Fu. Circ_0000215 Exerts Oncogenic Function in Nasopharyngeal Carcinoma by Targeting miR-512-5p . Frontiers in Cell and Developmental Biology, 2021, 9: 1-14.  (SCI IF:6.684)

四、Xinping Chen, HeQiu Ruan, Zhichao Ma, Junjie Hu, Weihua Xu, Liyan Yin, and Shengmiao Fu*. Polymerase Chain Reaction in the Detection of miR-455-5p and Sphingosine-1 Phosphate. Journal of Biomedical Nanotechnology, 2021, 17(8): 1535-1544. (SCI IF:4.099)

五、 Xinping Chen, Tao Wu, Lingguo Li, Yu Lin, Zhichao Ma, Jinjin Xu, Hui Li, Ruoyan Chen, Kun Sun, Yuxue Luo, Chen Zhang, Fang Chen, Jiao Wang, Tingyu Kuo, Xiaojuan Li, Chunyu Geng, Feng Lin, Chaojie Huang, Junjie Hu, Jianhua Yin, Ming Liu, Ye Tao, Jiye Zhang, Rijing Ou, Huanming Yang, Jian Wang, Xun Xu, Shengmiao Fu*, Hongyan Jiang*, Xin Jin* and Haiqiang Zhang*. TSS Coverage Analysis in Plasma Cell-free DNA Reveals Disease Severity and Tissue Specificity of COVID-19 Patients. Frontiers in Genetics, 2021, 12: 1-11. (SCI IF:4.599)

六、Xinping Chen, Zhangli Lin, Junjie Hu, Shiping Chen, Shu Wen, Aizhu Wu, HongWu, Jiali Huang, Hanqiang Wang, Jun Sun, Zhiyu Peng, Yan Sun* & Shengmiao Fu*. Report of Two Novel Thalassemia Variants, HBB:c.181delG and HBA1: c.121_126delAA GACC, in Chinese Individuals. Hemoglobin, 2021, 45(1):52-55. (SCI IF:0.53)

七、Xinping Chen, Zhichao Ma, Juan Zhu, Weihua Xu, Junjie Hu, Liyan Yin* and Shengmiao Fu*. Study on the antitumor activity and mechanism of novel targeted nanodrugs based on miRNA in cervical cancer. Materials Express, 2020,10 (8):1218-1223. (SCI IF:1.65)

八、XinPing Chen, JunJie Hu, Juan Zhu, WeiHua Xu, HongXia Yao, AiZhu Wu, MeiFang Xiao, Zhe Lu, LiYan Yin*, ShengMiao Fu*. Severe Hemolytic Anemia due to combined α thalassemia and de novo Hemoglobin Sabine. Annals of Hematology, 2019, 98(3): 783-785. (SCI IF: 2.85)

九、Xin-Ping Chen, Hai-Feng Wen, Fan Zhang, Wei-Hua Xu, Zhi-Chao Ma, Sheng-Miao Fu*. Assessment of the Link between XRCC1 Arg399Gln Polymorphism and Breast Cancer: a Meta-Analysis in a Single Ethnic Group. Clin. Lab, 2017;63:725-731. (SCI IF:1.1)

十、Xingping Chen, Weihua Xu, Dafeng Xu, Shengmiao Fu*, Zhichao Ma. G12V KRAs mutations in cervical cancer under virtual microscope of molecular dynamic simulations. European journal of gynaecological oncology. 2016,1:69-74 .(SCI IF:0.9)

十一、Xin-Ping Chen, Da-Feng Xu, Wei-Hua Xu, Zhi-Chao Ma, Jia Yao, Sheng-Miao Fu*. Association studies of CYP1A1 exon7 polymorphism and -GSTM1 interaction with esophageal cancer risk: a meta-analysis in the Chinese population. Clin. Lab, 2016, 62: 1795-1802. (SCI IF:1.1)

十二、Chen XP, Xu DF, Xu WH, Yao J, Fu SM*. Glutathione-S-transferases M1/T1 gene polymorphisms and endometriosis: a meta-analysis in Chinese populations. Gynecol Endocrinol, 2015, 31(11): 840–845. (SCI IF:1.33)

十三、Xin-Ping Chen, Wei-Hua Xu, Da-Feng Xu, Xian-He Xie, Jia Yao, Sheng-Miao Fu*. GSTM1 polymorphism and lung cancer risk in the Chinese population: A meta-analysis based on 47 studies. APJCP, 2014,15(18), 7741-7746. (SCI IF:1.5)

十四、Hongxia Yao*, Xingping Chen, Lie Lin, Congming Wu, Xiangjun Fu, Hua Wang, Zhiming Yao. The spectrum of α- and β-thalassemia mutations of the Li people in Hainan Province of China. Blood Cells. Molecules and Diseases, 2014, 53, 16-20. （共同第一作者）(SCI IF:2.39)